Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity connected to bortezomib, a proteasome inhibitor Employed in the procedure of numerous myeloma. Its synthesis or review is crucial for making sure the purity and safety with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Employed in the treatment of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A important compound during the synthesis of imatinib, a drug that targets precise forms of most cancers, which include Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers including breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their study is important for optimizing the generation method and ensuring substantial purity.
Lapatinib Intermediate D-Gluconic acid (CAS NO. 231278-eighty four-5): Lapatinib is applied to treat breast cancer, and these intermediates are associated with its manufacturing.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist used in the cure of breast cancer. Different intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug productive in 17b)-7-[9-[(4 managing cancers including ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the cure of colorectal most cancers and compact cell lung cancer.
3-Amino-one-hydroxyadamantane (CAS 702-82-nine): This compound is linked to the synthesis of adamantane derivatives, that have numerous applications, like antiviral Houses.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for style 2 diabetic issues that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved in the synthesis of assorted gluconic acid derivatives, which can be Utilized in foodstuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication employed to handle kind 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).